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CopomuS - Compensatory mutation selector

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CopomuS - Compensatory mutation selector

CopomuS evaluates and ranks possible compensatory point mutations within IntaRNA mfe predictions to guide respective validation experiments.

For articles describing the tool and webserver refer to the reference section below. Please cite us when using our tools.
For more information check the help page.

Try CopomuS with this example: RybB-tsx (Papenfort et al., 2010) (input|result)

When using CopomuS please cite :

Martin Raden, Fabio Gutmann, Michael Uhl, and Rolf Backofen
CopomuS - ranking compensatory mutations to guide RNA-RNA interaction
International Journal of Molecular Sciences, 21(11),3852, 2020.
Martin Mann, Patrick R. Wright, and Rolf Backofen
IntaRNA 2.0: enhanced and customizable prediction of RNA–RNA interactions
Nucleic Acids Research, 2017, 45 (W1), W435–W439.
Martin Raden, Syed M Ali, Omer S Alkhnbashi, Anke Busch, Fabrizio Costa, Jason A Davis, Florian Eggenhofer, Rick Gelhausen, Jens Georg, Steffen Heyne, Michael Hiller, Kousik Kundu, Robert Kleinkauf, Steffen C Lott, Mostafa M Mohamed, Alexander Mattheis, Milad Miladi, Andreas S Richter, Sebastian Will, Joachim Wolff, Patrick R Wright, and Rolf Backofen
Freiburg RNA tools: a central online resource for RNA-focused research and teaching
Nucleic Acids Research, 46(W1), W25-W29, 2018.

Results are computed with CopomuS version dev using IntaRNA 3.1.5