Freiburg RNA Tools
RaSE - Point mutation evaluator
BIF
IFF
RaSE

RaSE - Point mutation evaluator

RaSE uses the graph vectorization technique of EDeN to compute a score indicative of the structural stability responsibility of each nucleotide in an RNA sequence. The score is computed as the similarity of the structure obtained by changing a single nucleotide with respect to the original structure. The structure is based on RNAplfold base pair probabilities and thus reflects the overall structural ensemble accessible to the RNA molecule. Per sequence position, only the mutation that yields the largest structural difference is reported.

For articles describing the tool refer to the reference section below. Please cite us when using our tools.
For more information check the help page.

Input

?

Output

?

?
?
?

?
?
?

?
?

? Description:
? Your Email:
(optional)
(optional)

Results are computed with RaSE version 1.0.0 using VRNA 2.2.10 and EDeN 2.0